PAPER: DNA origami: a quantum leap for self-assembly of complex structures

Tørring, T.; Voigt, N. V.; Nangreave, J.; Yan, H.; Gothelf, K. V.

Chem. Soc. Rev. 2011, 40, 5636-5646.

Danish National Research Foundation: Centre for DNA Nanotechnology, at the Interdisciplinary Nanoscience Center and the Department of Chemistry, Aarhus University, Langelandsgade 140, 8000 Aarhus C, Denmark
Department of Chemistry and Biochemistry & The Biodesign Institute, Arizona State University, Tempe, AZ, USA

Abstract

The spatially controlled positioning of functional materials by self-assembly is one of the fundamental visions of nanotechnology. Major steps towards this goal have been achieved using DNA as a programmable building block. This tutorial review will focus on one of the most promising methods: DNA origami. The basic design principles, organization of a variety of functional materials and recent implementation of DNA robotics are discussed together with future challenges and opportunities.

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