Org Biomol Chem. 2014 Jun 14;12(22):3679-85. doi: 10.1039/c4ob00011k. Epub 2014 Apr 25.
Aarhus University, iNANO and Department of Chemistry, Gustav Wieds Vej 14, Aarhus, 8000, Denmark. email@example.com.
Homochiral tris-indanyl molecular rods designed for supramolecular surface self-assembly were synthesized. The chiral indanol moiety was constructed via a Ti-mediated alkyne trimerization. Further manipulations resulted in a homochiral indanol monomer. This was employed as the precursor for successive Sonogashira and Ohira-Bestman reactions towards the homochiral tris-indanyl molecular rods. The molecular rods will be applied for scanning tunnelling microscopy studies of their surface self-assembly and chirality.